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researchsquare; 2022.
Preprint in English | PREPRINT-RESEARCHSQUARE | ID: ppzbmed-10.21203.rs.3.rs-1374849.v1

ABSTRACT

Purpose: Covid-19 infection has been spreading across the globe since the end of 2019 and it continues to cause chronic multi-system sequalae, of which thyroid dysfunction appears to be a major one. We aim to present cases Methods: : Case series report. Results: : Over the period from October 2020 to July 2021, a series of 10 cases of thyroid dysfunction due to Covid-19 infection were seen and managed in a single outpatient endocrine centre in Doha, Qatar. These are 6 cases of Graves hyperthyroidism, two cases of chronic primary hypothyroidism including one with GD treated by RAI therapy, two cases of subacute thyroiditis and one case with ‘Thyroxin Thyrotoxicosis’, and finally one case of central hypothyroidism. Conclusion: This report is the largest to be reported from a single centre so far, and it points to a bimodal distribution of thyroid dysfunction in patients with covid-19 infection. A review of the literature and discussion of possible pathophysiological mechanisms is presented. We stress the importance of screening for thyroid dysfunction in post-Covid cases, as the prevalence may be underestimated.


Subject(s)
Thyrotoxicosis , Gaucher Disease , Thyroiditis, Subacute , COVID-19 , Congenital Hypothyroidism , Thyroiditis , Graves Disease , Hypothyroidism
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